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Process for stereosectively preparing optically ac

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专利内容由知识产权出版社提供

专利名称:Process for stereosectively preparing

optically active compounds

发明人:Rene Imwinkelried,Dieter Seebach申请号:US06/906736申请日:19860909公开号:US04812476A公开日:190314

摘要:An aldehyde (R.sup.1 CHO) and optically active 3- hydroxybutyric acid (CH.sub.3CH(OH)CH.sub.2 COOH) are reacted to form an optically active dioxanone. This dioxanoneis reacted with a compound R. sup.2 --X to form an intermediate (R.sup.1 R.sup.2CHOCH(CH.sub.3) CH.sub. 2 COOH) which is then subjected to elimination to form anoptically active secondary alcohol (R.sup.1 R.sup.2 CHOH) in good yield and purity.

申请人:IMPERIAL CHEMICAL INDUSTRIES PLC

代理机构:Cushman, Darby & Cushman

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